Flow synthesis of a versatile fructosamine mimic and quenching studies of a fructose transport probe

• Matthew B. Plutschack,
• D. Tyler McQuade,
• Giulio Valenti and
• Peter H. Seeberger

Beilstein J. Org. Chem. 2013, 9, 2022–2027, doi:10.3762/bjoc.9.238

• NBDM, enabling us to measure key photophysical properties that will facilitate future uptake studies. Keywords: flow chemistry; fructose mimic; gluts; NBDM; Introduction The impact of dietary fructose on human health is not well-understood. A growing body of work suggests that those eating diets high

• NBDM quenching was observed even at sugar concentrations as high as 100 mM. Conclusion In conclusion, we report the flow synthesis of the fluorescent fructose mimic NBDM. While we demonstrated for the first time that resin-supported nitrite ions can facilitate Tiffeneau–Demjanov rearrangements, we